![]() ![]() “That’s when I gave the condition the name of primary progressive aphasia,” said Mesulam, who is now the founder and director of the Mesulam Center for Cognitive Neurology and Alzheimer’s Disease at Northwestern University Feinberg School of Medicine. PPA also is known as Mesulam’s disease. ![]() What was causing this language disruption, he wondered? But in 1982, he started seeing individuals who had difficulty with language who hadn’t had a stroke or been diagnosed with dementia. Mesulam in the 1980s was running a behavioral neurology unit at Harvard Medical School where he saw patients with dementia - then singularly defined as “having memory loss” - or who had had a stroke, which, at the time, was the only recognized cause of language disturbance. Marsel Mesulam was pioneering a new field of research on a similar neurological condition: primary progressive aphasia (PPA), a rare, overlooked and underserved syndrome that destroys a person’s language. Decades before the world learned about Bruce Willis’ aphasia diagnosis, Dr.
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